In the US, about 16 million adults struggle with major depressive disorder every year, with costs skyrocketing to around $210 billion. Though we think of depression as mainly affecting the mind, it is increasingly being understood as a complex condition that has physical effects throughout the body.
One growing avenue in comprehending and addressing mental illnesses involves looking cellular metabolism markers, offering promising pathways for improved diagnosis, treatment, and prevention strategies.
Researchers at University of California San Diego School of Medicine have now advanced this line of work in a new study, revealing a connection between cellular metabolism and depression. Those battling treatment resistant depression and having suicidal thoughts often have certain compounds in their bloodstream, which could show who’s more likely to be at risk for suicide.
The study suggested we could identify around up to 90% of individuals at the highest risk based on just five specific compounds in males and another set of five in females. This could become a game-changer in terms of diagnosis and maybe even understanding what causes these changes in our bodies.
🌀 The Miracle of Mitochodria
Why focus on the blood? Well, turns out, our cell energy factories, called mitochondria, play a huge role. When these mitochondria go haywire, it messes with our cells’ energy and communication systems. Think of it like a warning signal gone awry inside our body.
This study suggests that suicidal thoughts might actually be part of a larger bodily impulse to stop a stress response that’s become too much for our cells to handle.
The study hints at supplements like folate and carnitine, which could help fix these metabolic gaps. No, they’re not magic fixes, but they might give a helpful push towards better treatment outcomes. When it comes to stopping suicide, these little shifts could be crucial.
But this isn’t only about depression. If we can figure out the cell problems, we could have major success in treating many long-term illnesses that are often seen with depression. Onward!!
Peter Zafirides, MD
Central Ohio Behavioral Medicine
PSYCHIATRY
COLUMBUS, OHIO
If you’re experiencing anxiety or depression do not take these symptoms lightly. The earlier you get help, the quicker you can find healing, because your symptoms truly can get better. Working with our psychiatrists is a proven path for dealing with such concerns. Contact us to talk about getting you the help you need and deserve.
